Flexeril vs Methocarbamol Comparison

If you or anyone you know is undergoing a severe health crisis, call a doctor or 911 immediately. Both of these drugs work similarly, which also means that most of the side effects of Flexeril vs. Baclofen are the same. Some side effects are unique to the specific drug and how it reacts in the patient’s body. In this blog post, we’ll explore some key differences between both medications to help you determine which option would offer better relief for your condition. Yes, one of the common side effects of Flexeril is drowsiness, which can make you feel sleepy or tired.

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Calls to our general hotline may be answered by private treatment providers. We may be paid a fee for marketing or advertising by organizations that can assist with treating people with substance use disorders. Because of the similarities between the two drugs, there’s often a question of which one between Flexeril vs. Baclofen is stronger. Abusing this drug increases the risk of anticholinergictoxidrome, as the acetylcholine builds up in the system due to the blockage of its receptors. It’s important to understand that using any medication for non-medical purposes, especially with the intention of achieving a high, can be dangerous and should be avoided.

You are encouraged to report negative side effects of prescription drugs to the FDA. It is intended for general informational purposes and is not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911. Since Robaxin and Flexeril have CNS depressant effects, they can interact with other drugs that have similar effects.

Shoulder and Neck Pain

The most common adverse effects included drowsiness, dry mouth, and dizziness. Cyclobenzaprine is a centrally acting skeletal muscle relaxant structurally related to tricyclic antidepr[7]essants. Cyclobenzaprine relieves skeletal muscle spasms of local origin without interfering with muscle function. In preclinical research, cyclobenzaprine reduced skeletal muscle hyperactivity. Research indicates that it primarily acts within the central nervous system in the brain stem. Selection of a skeletal muscle relaxant should be individualized to the patient.

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This medication can also negatively interact with alcohol and a host of other medications to produce annoying to serious side effects. If you do not drink or take other medications, this may not seem like a dire warning. This drug creates a physical dependency when people abuse it and over time, they may need it to sleep or even function normally. The “Cyclobenzaprine high” refers to the pleasurable and sometimes euphoric sensations that individuals might experience when misusing cyclobenzaprine, often for recreational purposes. The Diffucaps beads contained in each CER capsule are made by coating an inert core (such as sugar) with a layer of the active drug, cyclobenzaprine, and then by applying a seal coat and rate-controlling membrane.

Medications & Supplements

Baclofen withdrawal can be life-threatening with possible multi-organ failure and psychological symptoms (2, 12). The study quality was assessed independently in duplicate, with substantial interrater agreement (κ, 0.79). Objective  To perform a systematic review of cyclobenzaprine’s effectiveness in the treatment of back pain. Cyclobenzaprine is structurally and pharmacologically related to tricyclic antidepressants. Among the most dreaded toxicities linked with cyclical antidepressants, overdoses affect fast-acting sodium channels in the cardiac conduction system. Cyclical antidepressants block the cardiac sodium channel and cause prolongation of cardiac depolarization, which manifests as QRS widening on electrocardiograms.

  • The patient should rinse their mouth to ensure that they have swallowed all the contents.
  • It is structurally similar to the tricyclic antidepressants and adverse effects similar to those seen with the tricyclic antidepressants are therefore to be expected.
  • A final limitation is that, in the real world, clinicians are not limited to just 1 treatment option.
  • Its actions on the CNS may also cause some of this medicine’s side effects.

If you don’t have insurance, you can use a SingleCare discount card to cut this cost to less than $8 depending on your pharmacy. Even if you do have insurance, it may be a good flexeril and advil idea to find out if you can get a cheaper price on muscle relaxants. Those who are prescribed Robaxin tablets need to take two or three tablets four times per day, initially.

Drug comparisons between cyclobenzaprine and methocarbamol in terms of side effects do not reveal many differences. Both medications can cause adverse effects such as dizziness, drowsiness, headache, nausea, and fatigue. Also, cyclobenzaprine can cause dry mouth because it has anticholinergic effects. Addiction Resource is an educational platform for sharing and disseminating information about addiction and substance abuse recovery centers. Addiction Resource is not a healthcare provider, nor does it claim to offer sound medical advice to anyone.

The daily dose ranged from 10 to 60 mg, titrated based on the adverse effects, with a median dose of 30 mg/d. One study21 used a twice-daily dose of cyclobenzaprine, and the remainder of the studies18,22,24,25,30-37 used 3 times daily doses. The study duration averaged 12.3 days, ranging from 7 to 18 days (median, 14 days). Skeletal muscle relaxants are prescription medications commonly used to treat muscle pain and muscle spasms. If you have back pain or have suffered a strain or sprain, your healthcare provider may offer you a skeletal muscle relaxant such as methocarbamol (Robaxin) or cyclobenzaprine (Fexmid, Amrix). Conservative treatment, such as physical therapy, exercise, and NSAIDs, should always be the first choice for remedying muscle spasms and related pain.

Comparison studies have not shown one skeletal muscle relaxant to be superior to another. Cyclobenzaprine is the most heavily studied and has been shown to be effective for various musculoskeletal conditions. The sedative properties of tizanidine and cyclobenzaprine may benefit patients with insomnia caused by severe muscle spasms. Methocarbamol and metaxalone are less sedating, although effectiveness evidence is limited. Adverse effects, particularly dizziness and drowsiness, are consistently reported with all skeletal muscle relaxants.

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